Hundreds of protesters took to New York City’s streets Friday night to demonstrate against police brutality in the wake of George Floyd's death in Minneapolis, after at least 70 people were arrested in a similar rally Thursday.

Footage from the scene showed at least four people being led from the 88th Precinct in a handcuffed chain, as officers formed a perimeter around the entrance to protect it. The NYPD confirmed at least 50 arrests Friday, and multiple cops were believed to have been injured.

Though they started relatively calmly, as night fell the protests escalated dramatically -- particularly in Brooklyn, where videos showed police vehicles burning and officers physically clashing with protesters. Hours after holding a news conference to call for peaceful demonstration, Mayor Bill de Blasio acknowledged the situation was anything but.

But in a twist, after social media posts showed the police commandeering an MTA bus to transport protesters and the driver resisting, the Transport Workers Union tweeted that its members should refuse to drive the arrested.